May 5, 2026

Social impairments common to those with 22q11.2 deletion syndrome, previously known as DiGeorge syndrome, can resemble symptoms of autism. As a result, many children with this condition, estimated to be as high as 50%, are classified with autism spectrum disorder. However, the two conditions may be unrelated because treatments designed for those with autism may exacerbate anxiety among individuals with 22q11.2 deletion syndrome.

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Children with autism wake up more frequently and sleep less than their typically developing peers. Night-time sleep duration was shortened by later bedtimes and earlier waking times. Frequent waking (three or more times a night) was also evident among the children with ASD from 30?months of age. These sleep problems may contribute to learning and behavior issues, and they may be related to brain differences that affect their biological clocks.

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